Fig. 7: Clinical relevance of Nkx2.8 and Twist1 in human UC. | Cell Death & Disease

Fig. 7: Clinical relevance of Nkx2.8 and Twist1 in human UC.

From: Nkx2.8 promotes chemosensitivity in bladder urothelial carcinoma via transcriptional repression of MDR1

Fig. 7: Clinical relevance of Nkx2.8 and Twist1 in human UC.

A Nkx2.8 levels were negatively associated with P-gp expression in 246 human UC specimens. Three representative cases are shown (scale bar, 200 μm). B Percentage of UC specimens showing negative or positive Nkx2.8 expression relative to the level of P-gp. p values are indicated (chi-square test). C Comparison of the RFS times of NMIBC patients with different levels of Nkx2.8 and P-gp expression combination. p values are indicated (log-rank test). D Comparison of the PFS times of NMIBC patients with different levels of Nkx2.8 and P-gp expression combination. p values are indicated (log-rank test).

Back to article page