Fig. 7

The schematic diagram shows the proposed mechanism that cAMP activates β-catenin through PKA and GSK3β, and afterwards promotes transcription of the downstream genes APELA and CARD16, which eventually prevent neuronal differentiation in GSCs.

The schematic diagram shows the proposed mechanism that cAMP activates β-catenin through PKA and GSK3β, and afterwards promotes transcription of the downstream genes APELA and CARD16, which eventually prevent neuronal differentiation in GSCs.