Fig. 3: Reduction of FMRP impairs proliferation of GSCs.
From: FMRP modulates the Wnt signalling pathway in glioblastoma
A Growth curves of GSCs transduced with either shNTC or shFMR1 (as indicated on top of each graph). The percentage of cell viability is plotted against days in culture (mean ± SEM, n = 3, two-way ANOVA). B The percentage of BrdU incorporation in the shFMR1 compared to shNTC GSCs (mean ± SEM, n = 3, ***P < 0.001, Student’s t-test). C Growth curves of GSC#1 transduced with the empty vector (CTRL) or with the vector overexpressing FMRP (+FMR1). The percentage of cell viability is plotted against days in culture (mean ± SEM, n = 3, *P < 0.05, ***P < 0.001, two-way ANOVA).
