Fig. 5: Overexpression of MGMT reversed circWDR62 knockdown-induced TMZ resistance and malignant progression of glioma cells. | Cell Death & Disease

Fig. 5: Overexpression of MGMT reversed circWDR62 knockdown-induced TMZ resistance and malignant progression of glioma cells.

From: Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma

Fig. 5

U343-R and U251-R cells were transfected with shRNA-NC or shRNA-circWDR62 and MGMT vector or empty vector. A The IC50 of TMZ was measured by the CCK-8 assay. B The EdU assay was performed to assess cell proliferation. C, D Transwell assays were performed to assess cell invasion (C) and migration (D).

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