Fig. 6: The DA-MeHA hydrogel regulated Notch signaling.

A–E DA-MeHA hydrogel-encapsulated spheroids or suspensions of ADSCs upregulated the expression of Notch1 and Notch2 while downregulating the expression of Notch3, Jagged1 and Jagged2. F No significant difference in Hes1 expression was observed among the groups. n = 4 samples/group (*p < 0.05 and **p < 0.01).