Fig. 7: ANRIL mediated endothelial dysfunction by recruiting EZH2 to the promoter region of BDNF. | Cell Death & Disease

Fig. 7: ANRIL mediated endothelial dysfunction by recruiting EZH2 to the promoter region of BDNF.

From: LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease

Fig. 7

A The protein expression of vWF, eNOS, VCAM-1, Mfn2 and Drp1 in HUVECs. B, C The expression of VCAM-1 and Mfn2 was detected by immunofluorescence assay. Scale bars = 50 μm. D Mitosox Red staining showed the ROS level in mitochondria of endothelial cells. Scale bars = 50μm. Data were shown as mean ± SD (n = 3). (one-way ANOVA and the Tukey post-test. *P < 0.05 versus respective control, #P < 0.05 versus ANRIL overexpression). ANR: ANRIL overexpression, BDNF: BDNF overexpression.

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