Fig. 7: Inhibition of mitochondrial fission reversed NDUFA4-mediated effects in GC.
From: m6A RNA methylation-mediated NDUFA4 promotes cell proliferation and metabolism in gastric cancer
A Cell viability, (B) ECAR, (C) OCR, (D) lactate and (E) ATP content of MKN45 cells with NDUFA4 overexpression and/or 20 μM Mdivi-1. MKN45 cells transduced with NDUFA4 expression vector were subcutaneously injected into the armpits of the mice with or without 25 mg/kg Mdivi-1 treatment. F Tumor volume in each group. G The photograph of xenografts. H Tumor weight in each group. ***P < 0.001.
