Fig. 3: NXN suppressed the proliferation and metastasis of HCC cells in vivo. | Cell Death & Disease

Fig. 3: NXN suppressed the proliferation and metastasis of HCC cells in vivo.

From: NXN suppresses metastasis of hepatocellular carcinoma by promoting degradation of Snail through binding to DUB3

Fig. 3

NXN overexpression suppressed the proliferation of HCC cells in nude mice. Tumors volume (A) and tumor weight (B) after subcutaneous injection of indicated Hepa1-6 cells. Four mice per group. NXN overexpression suppressed metastasis of HCC cells in nude mice. Representative images of metastatic lung tumors (gross and HE staining) and quantification in NXN overexpression (C) and NXN knockdown group (D) after tail vein injection. Scale bar, 100 µm. Five mice per group. *P < 0.05, Student’s t-test.

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