Fig. 6: The HOXA11-AS/miR-148b-3p/SLC2A1 axis is essential for FOXD1-mediated PC progression. | Cell Death & Disease

Fig. 6: The HOXA11-AS/miR-148b-3p/SLC2A1 axis is essential for FOXD1-mediated PC progression.

From: FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis

Fig. 6

PC cells infected with FOXD1-overexpressing lentivirus were co-transfect with si-HOXA11-AS, miR-148b-3p mimics, and si-SLC2A1. A, B ECAR and OCR were employed to measure the level of aerobic glycolysis in each group. C, D CCK8 and EdU staining were employed to evaluate the proliferation capacity. E Transwell assays were performed to evaluate the invasive and metastatic capacities. *p < 0.05; **p < 0.01.

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