Fig. 1: Single-cell transcriptional profiling of PBMCs derived from IR and INR patients with HIV-1-infected.

A Two-dimensional UMAP visualization of PBMCs for IRs and INRs. Different colors represent different sample sources. B Different colors represent 10 clusters (cell types) defined by the k-means clustering algorithm. Different colors represent 11 cell types. The UMAP projection of 12086 single cells from IR and INR samples shows 11 clusters with the respective labels. Each dot corresponds to a single cell, colored according to cell type. C, D Stacked violin plots showing the expression distribution of selected canonical cell markers in the CD8 MAIT T cells.