Fig. 6: Profile of CD8 effector T cells in INRs.

A UMAP visualization of CD8 effector T cells using the Seurat R package. Different colors represent two groups (left). Different colors represent different cell subsets (right) (B). C Proportion of CD8 effector T cells. D Differentially expressed genes in CD8 effector T cells between IRs and INRs ©. E Heatmap of top 40 genes significantly expressed in CD8 effector T C1. F Heatmap of top 40 genes expressed in CD8 effector T C2. G GO and KEGG were analyzed using DAVID for upregulated genes in CD4 CTL cells from INRs compared with IRs.