Fig. 7: Altered behaviour of non-myogenic mesenchymal progenitors in FSHD patients’ muscles. | Cell Death & Disease

Fig. 7: Altered behaviour of non-myogenic mesenchymal progenitors in FSHD patients’ muscles.

From: Non-myogenic mesenchymal cells contribute to muscle degeneration in facioscapulohumeral muscular dystrophy patients

Fig. 7

An excessive accumulation, as well as an aberrant differentiation of non-myogenic mesenchymal progenitors can be observed in FSHD patients’ muscles in which the active phase of the disease is identifiable by muscle MRI. Although the causes of non-myogenic mesenchymal progenitors’ dysregulation are not clear, this process might lead to muscle wasting of selected muscles in FSHD patients. (Created with BioRender.com).

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