Fig. 4: Gene ontology (GO) and pathway analyses. | Cell Death & Disease

Fig. 4: Gene ontology (GO) and pathway analyses.

From: Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles

Fig. 4

Canonical pathways associated with human gene expression changes by RNA-Seq in infected NOKs and infected PBMCs at 7days and 15days when compared to the mock infected cells. A Gene ontology (GO) analyses. Bar charts are shown for GO Slim analysis terms for differentially transcribed protein-coding genes showing a change in both infected NOKs and infected PBMCs compared to no infected cells. B–E Gene set enrichment analysis (GSEA) for KEGG pathways identified from differentially transcribed protein-coding genes after BAC GFP-EBV infection. KEGG pathways are plotted against their average normalized enrichment score, showing upregulated (orange) and downregulated (blue) pathways. The width of the bars reflects the p-value, and the boxes reflect the ratio of the number of genes in the data set represented in the pathway.

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