Table 1 Correlation between the CD206+ TAMs and clinical parameters (n = 72).

From: NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer

Parameters

No. (%)

CD206 expression

All

low

high

aP

Age

59 ± 9.11

57 ± 8.56

61 ± 9.45

0.121

Female

11 (15.3%)

5 (13.9%)

6 (16.7%)

0.743

Smoking

17 (23.6%)

9 (25%)

8 (22.2%)

0.781

Tumor site

Left lung

35 (48.6%)

18 (50%)

17 (47.2%)

0.814

Right lung

37 (51.4%)

18 (50%)

16 (52.8%)

 

Tumor size, cm

≥5

27 (37.9%)

12 (33.3%)

15 (41.7%)

0.523

<5

45 (62.1%)

24 (66.7%)

21 (58.3%)

 

Tumor stage

Limited stage

59 (81.9%)

31 (86.1%)

28 (77.8%)

0.358

Extensive stage

13 (18.1%)

5 (13.9%)

8 (22.2%)

 

Metastasis

56 (77.8%)

24 (66.7%)

32 (88.9%)

0.023*

Overall

72 (100%)

36 (50%)

36 (50%)

 
  1. Data were expressed as average ± standard deviation (SD) for continuous variables and count (percentage) for categorical variables. Boldface type indicates statistical significance.
  2. aP-values indicate differences between CD206-high and CD206-low expressed patients.
  3. *P < 0.05.
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