Table 3 Comparison of clinical characteristics in high SOCS5 patients with the pringle maneuver time less than or over 15 min*.

From: SOCS5 knockdown suppresses metastasis of hepatocellular carcinoma by ameliorating HIF-1α-dependent mitochondrial damage

Characteristics

Pringle maneuver time <15 min

Pringle maneuver time ≥15 min

p value

N

40 (64.5)

22 (35.4)

 

Age, years

  

0.72a

≤60

29 (72.5)

15 (68.2)

 

>60

11 (27.5)

7 (31.8)

 

Sex

  

0.238b

Male

30 (75.0)

20 (90.9)

 

Female

10 (25.0)

2 (9.1)

 

HBsAg

  

0.546c

Negative

39 (7.5)

0 (0.0)

 

Positive

37 (92.5)

22 (1.0)

 

Cirrhosis

  

0.821a

Yes

28 (70.0)

16 (72.7)

 

No

12 (30.0)

6(27.3)

 

AFP, ng/ml

  

0.419a

≤400

26 (65.0)

12 (54.5)

 

>400

14 (35.0)

10 (45.5)

 

Tumor size, cm

4 (2.63–6.38)

5.88 (33.88–7.13)

0.068d

Tumor number

  

0.159b

Solidary

36 (90.0)

16 (72.7)

 

Multiple

4 (10.0)

6 (27.3)

 

Microvascular invasion

  

0.533a

Yes

14 (35.0)

6 (27.3)

 

No

26 (65.0)

16 (72.7)

 

Macroscopic vascular invasion

  

0.159b

Yes

4 (10.0)

6 (27.3)

 

No

36 (90.0)

16 (72.7)

 

Tumor capsule

  

0.188b

Yes

3 (7.5)

5 (22.7)

 

No

37 (92.5)

17 (77.3)

 

Tumor differentiation

  

1b

I-II

35 (87.5)

19 (86.4)

 

III-IV

5 (12.5)

3 (13.6)

 

Steatosis

  

1c

Yes

2 (5.0)

1(4.5)

 

No

38 (95.0)

21 (95.5)

 

Blood loss, ml

200 (100–375)

200 (200–550)

0.057d

Blood transfusion

  

0.601b

Yes

4 (10.0)

4 (18.2)

 

No

36 (90.0)

18 (81.8)

 
  1. AFP α-fetoprotein, SOCS5 suppressor of cytokine signaling 5.
  2. *Continuous variables were presented as median (Q1–Q3) and tested by the Mann–Whitney U-test. Categorical variables were expressed as numbers (%) and tested by the χ2 test, continuity correction by χ2 test, or Fisher’s exact test.
  3. aPearson’s χ2 test.
  4. bContinuity correction by χ2 test.
  5. cFisher exact test.
  6. dMann–Whitney U-test.
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