Fig. 2: TXNRD1 promotes proliferation and metastasis of HCC cells in vitro. | Cell Death & Disease

Fig. 2: TXNRD1 promotes proliferation and metastasis of HCC cells in vitro.

From: USF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling

Fig. 2: TXNRD1 promotes proliferation and metastasis of HCC cells in vitro.The alternative text for this image may have been generated using AI.

A Proliferation abilities of HCC cells with TXNRD1 knockdown compared to the control vector were investigated by cell growth curve and CCK-8 assay. B Proliferation abilities of HCC cells with TXNRD1 overexpression compared to the control vector were investigated by cell growth curve and CCK-8 assay. C The anchorage-depend colony formation assay was performed to assess the effects of TXNRD1 knockdown on clone formation ability of HCC cells. D The anchorage-depend colony formation assay was performed to assess the effects of TXNRD1 overexpression on clone formation ability of HCC cells. E Cells migration and invasion abilities in HCC cells with TXNRD1 knockdown were determined by transwell assay. Representative image (left) and summary bar chart (right) are shown. Scale bar, 200 μm. F Cells migration and invasion abilities in HCC cells with TXNRD1 overexpression were determined by transwell assay. Representative image (left) and summary bar chart (right) are shown. Scale bar, 200 μm. Data represent the mean ± SEM. ***P < 0.001. P values were calculated by One-way ANOVA (A, C, E) or Student’s t test (B, D, F).

Back to article page