Fig. 9: ADCK1 KO inhibits pOS-1 xenograft in situ growth.
From: ADCK1 is a potential therapeutic target of osteosarcoma
The sg-C expressing pOS-1 cells or the koADCK1 pOS-1 cells were injected to proximal tibia of the nude mice; After 30 days, in situ pOS-1 tumors were detected by X-ray, with its volumes recorded (A); Expression of listed genes in tumor lysates was shown (B, C), and ATP contents examined as well (E). The representative TUNEL-DAPI immuno-fluorescence images of the xenograft slides were presented (D), with TUNEL-positive nuclei ratio quantified (D). Data were presented as mean ± standard deviation (SD). *P < 0.05 vs. “sgC” group. Scale bar = 50 μm (D).
