Fig. 7: In vivo examination of the impact of NALT1 on cell growth and metastasis capability.
From: LncRNA NALT1 promotes colorectal cancer progression via targeting PEG10 by sponging microRNA-574-5p
A Representative images of the tumors after subcutaneous injection with NALT1-knockdown and NC HCT116 cells. B Tumor volume was analyzed in NALT1-knockdown/control group. C Representative images of immunofluorescence and H&E staining using antibodies against PEG10 and Ki-67. D Representative images of the tumors after subcutaneous injection with NALT1-overexpression and NC HCT116 cells. E Tumor volume was analyzed in the NALT1-overexpression/control group. F Representative images of immunofluorescence and H&E staining using antibodies against PEG10 and Ki-67. G After injection of NALT1-knockdown or overexpression HCT116 cells into the spleen of nude mice at five weeks, the lungs were isolated from the mice and the metastatic lung nodules were marked. H Representative images of lung tissue sections by H&E staining. I The number of metastatic nodules in the lungs.
