Fig. 3: Exosomal miR-197-3p promotes proliferation, angiogenesis and migration in HUVECs.

A Cell proliferation was monitored by CCK-8 assay. B Angiogenesis was measured by 3D spheroid sprouting assay. C Angiogenesis was assessed by tube formation assay with quantitative analysis (right panel). D Cell migration was assessed by wound healing assay with quantitative analysis (right panel). E Migration of HUVECs was monitored by transwell migration assay with quantitative analysis (right panel). Data were representative images or were expressed as the mean ± SD of n = 3 experiments. *P < 0.05, **P < 0.01, ***P < 0.001.