Fig. 5: Myeloid-specific deletion of Tsc2 induces Gpr68 expression in AngII-infused aortas. | Cell Death & Disease

Fig. 5: Myeloid-specific deletion of Tsc2 induces Gpr68 expression in AngII-infused aortas.

From: Loss of myeloid Tsc2 predisposes to angiotensin II-induced aortic aneurysm formation in mice

Fig. 5

A, B Quantitative real-time PCR (n = 5) and western blot (n = 4) were performed to determine the expression of Gpr68 in abdominal aortas from AngII-infused Tsc2MKOApoE–/– and Tsc2WTApoE–/– mice on day 28. C Immunofluorescence staining of F4/80 (red) and Gpr68 (green) in abdominal aortic tissues from AngII-infused Tsc2MKOApoE–/– and Tsc2WTApoE–/– mice on day 28 (n = 5). Scale bar = 50 µm. *P < 0.05, vs. Tsc2WTApoE–/– mice infused with AngII.

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