Fig. 5: Cigarette smoke exposure shows no significant effect on MFG-E8 mRNA levels in vivo and in vitro. | Cell Death & Disease

Fig. 5: Cigarette smoke exposure shows no significant effect on MFG-E8 mRNA levels in vivo and in vitro.

From: MFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells

Fig. 5

A MFG-E8 RNA levels in small airway epithelium were similar between 28 samples of non-smokers and 58 samples of smokers from GEO Profiles. B MFG-E8 RNA levels in human lung tissues were similar between 12 samples with no or mild emphysema and 18 samples with severe emphysema from GEO Profiles. C MFG-E8 RNA levels in sputum were similar between 71 stage 2 COPD samples, 59 stage 3 COPD samples, and 13 stage-4 COPD samples from GEO Profiles. D Levels of MFG-E8 mRNA in lung tissues of COPD patients and healthy controls. E Levels of MFG-E8 mRNA in lung tissues of mice. Control: WT mice exposed to PBS. CSE: WT mice exposed to CSE. F Levels of MFG-E8 mRNA in BEAS-2B cells and HBE cells exposed to CSE. Data are presented as the mean ± SD.

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