Fig. 6: MFG-E8 is degraded by the proteasome.

A BEAS-2B cells were treated with 10 μg/ml CHX or 5 μM MG132 for various time points prior to immunoblotting analyses of MFG-E8 protein levels. B The densitometric changes of MFG-E8 protein expression in BEAS-2B cells were plotted. C HBE cells were treated with 20 μg/ml CHX or 10 μM MG132 for various time points prior to immunoblotting analyses of MFG-E8 protein levels. D The densitometric changes of MFG-E8 protein expression in HBE cells were plotted. Data are presented as the mean ± SD of three independent experiments.