Fig. 2: Alterations of cell marker proteins in the pancreatic islet of HuD KO mice.

Several marker proteins of pericytes (NG2), endothelial cells (PECAM-1), neutrophils (MPO), and macrophages (CD68) in the pancreatic tissues were analyzed by immunofluorescence microscopy. The nuclei were stained with DAPI solution. Fluorescent signals between wildtype (WT) and HuD knockout (KO) mice were quantified using the Image J program. Data indicate the mean ± SEM and images are representative. Scale bar, 50 μm. The statistical significance of the data was analyzed via Student’s t test; *p < 0.05.