Fig. 1: High expression of HN1L predicates poor prognosis in patients with ESCC. | Cell Death & Disease

Fig. 1: High expression of HN1L predicates poor prognosis in patients with ESCC.

From: HN1L/AP-2γ/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma

Fig. 1

A Double IF staining showed the cellular localization of HN1L in ESCC tissues. Pan-cytokeratin was used to indicate cancer cells. Scale bar, left 20 μm; right 5 μm. B Representative image of IHC staining for HN1L in a clinical sample with normal esophageal epithelial tissue and ESCC tissue. Scale bar in left panel, 300 μm; right panel, 20 μm. C IHC staining in the ESCC tissue array showed the different expression levels of HN1L. Scale bar, 100 μm. D Expression scores of HN1L in ESCC tissue array (n = 229). Data are presented as the mean ± SD; two-sided Student’s t test; ***P < 0.001. E Correlation analysis between HN1L expression and clinicopathological data. One-way ANOVA; *P < 0.05, ***P < 0.001. F Kaplan–Meier survival curves showed that a high level of HN1L was associated with poor prognosis in patients with ESCC.

Back to article page