Fig. 4: SLC1A5 modulated the glioma growth in vivo.

A The schematic illustration of U87 related cells transplantation in BALB/c nude mice. B The HE staining and the tumor size analysis for mice in SLC1A5 overexpression or knockdown groups (Scale Bar = 1 mm). C Kaplan–Meier survival curves of the mice survival time in SLC1A5 overexpression or knockdown groups. D The Ki-67 scores of glioma sections in SLC1A5 overexpression or knockdown groups. E The Ki-67 IHC images of glioma sections in SLC1A5 overexpression or knockdown groups (Scale Bar = 20 μm). F The schematic illustration of V9302 treatment in GL261-bearing C57BL/6 mice. G The HE staining and the tumor size analysis for mice in the control and V9302 groups (Scale Bar = 1 mm). H Kaplan–Meier survival curves of the survival time of mice in the control and V9302 groups. I The Ki-67 IHC images and scores of glioma tissues in the control and V9302 groups (Scale Bar = 20 μm).