Fig. 3: Increased somatic accumulation of α-syn in the rats injected with intestine or vagus lysate.

α-syn is immunoreactive in the neurons and neurites of host midbrain SN (a) and STR (b) in the rats intrastriatally injected with PBS, intestine lysate, or vagus lysate derived from a post-mortem PD patient. Arrows point to dopaminergic neurons containing a large number of pigmented granules. Scale bars, 200 μm; high-magnification, 20 μm. L ipsilateral left brain, R contralateral right brain.