Fig. 6: Hsa_circ_0021727 promotes the metastasis and proliferation of ESCC cells in vivo by regulating the expression of miR-23b-5p. | Cell Death & Disease

Fig. 6: Hsa_circ_0021727 promotes the metastasis and proliferation of ESCC cells in vivo by regulating the expression of miR-23b-5p.

From: Hsa_circ_0021727 (circ-CD44) promotes ESCC progression by targeting miR-23b-5p to activate the TAB1/NFκB pathway

Fig. 6

A Image showing the subcutaneous xenograft tumor tissues injected with KYSE510 cells co-transfected with miR-23b-5p and hsa_circ_0021727 overexpression vectors. B Graphs of tumor volumes in subcutaneous xenograft tumor models. C Image of lung metastatic nodules. Nude mice were injected with KYSE510 cells co-transfected with miR-23b-5p and hsa_circ_0021727 overexpression vectors. D Statistical analysis of lung metastatic nodules. E Lung tissue was stained using HE. Values are expressed as the means ± SD; *P < 0.05.

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