Table 2 G4-targeting photosensitizers.

From: Crosstalk between G-quadruplex and ROS

 

G4 ligand

Target G4

Gene

Cell type

Porphyrin derivatives

TMPyP4 [105, 177, 182, 231]

DNA

KRAS

MCF-7 human breast cancer cells、HeLa cells

TMPipEOPP [179]

DNA

 

human colon carcinoma cells (HCT-8)

ZnP1 [180]

DNA

  
 

TMPyP4-C14 [106]

RNA

KRAS, NRAS

pancreatic cancer cells

Phthalocyanine derivatives

ZnAPC [181]

RNA

NRAS

MCF-7 human breast cancer cells

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