Fig. 6: IL18-hUCMSC did not have a better immunosuppressive effect on the expression of proinflammatory cytokines in serum and lung tissue. | Cell Death & Disease

Fig. 6: IL18-hUCMSC did not have a better immunosuppressive effect on the expression of proinflammatory cytokines in serum and lung tissue.

From: Interleukin-18-primed human umbilical cord-mesenchymal stem cells achieve superior therapeutic efficacy for severe viral pneumonia via enhancing T-cell immunosuppression

Fig. 6

A The protein level of pro-inflammatory cytokines (IFN-γ, TNF-α, IL-1β, and IL-6) in serum in different groups at 7 dpi were analyzed by ELISA kit. B The mRNA expression of IFN-γ, TNF-α, IL-1β, IL-6, and IL-10 in lung tissue was analyzed by qPCR. C The protein level of IFN-γ, TNF-α, IL-1β, and IL-6 in lung tissues in different groups at 7 dpi was analyzed by ELISA kit. Data are shown as mean ± SEM. n = 3–5 in each group. *p < 0.05, **p < 0.01, ***p < 0.001, ns = not significant.

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