Fig. 1: Dasabuvir inhibits ESCC cell proliferation in vitro. | Cell Death & Disease

Fig. 1: Dasabuvir inhibits ESCC cell proliferation in vitro.

From: Dasabuvir suppresses esophageal squamous cell carcinoma growth in vitro and in vivo through targeting ROCK1

Fig. 1

A KYSE450 cells were used to screen the cytotoxicity of 50 drugs (n = 3). The concentration of each drug was 50 μM. B Chemical structure of dasabuvir. C The effect of dasabuvir on the cell viability of KYSE150, KYSE450 cells. Cell viability was detected by DAPI staining (n = 3). D The effect of dasabuvir on the proliferation of KYSE150, KYSE450 cells. Proliferation ability was detected by DAPI staining (n = 3). E Representative images of anchorage independent cell growth assay (left) and quantitative analyses of colony numbers (right, n = 3). F Representative images of anchorage dependent cell growth assay (left) and quantitative analyses of colony numbers (right, n = 3). Data were analyzed by one-way ANOVA test and the asterisk indicated a significant (*p < 0.05, **p < 0.01 and ***p < 0.001) difference compared with the control group.

Back to article page