Fig. 3: List of PDOs and cell lines selected for a further assessment of ALT markers. | Cell Death & Disease

Fig. 3: List of PDOs and cell lines selected for a further assessment of ALT markers.

From: Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT)

Fig. 3

A The table lists the 7 PDOs studied for ALT markers, indicating microsatellite status, consensus molecular subtype (CMS), CRIS type together with mutational status in key oncogenes, tumor suppressors and the ALT-associated gene ATRX. B The table shows the 19 CRC cell lines characterized, indicating microsatellite status, consensus molecular subtype (CMS), CRIS type together with mutational status in key oncogenes, tumor suppressors and ATRX and DAXX alterations. C ATRX mRNA expression levels in CRC cell lines. OUMS23 cell line showed the lowest level of ATRX expression and was included in our screens.

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