Fig. 2: Protein networks associated with 56 enriched MEF2A interactors.
From: The MEF2A transcription factor interactome in cardiomyocytes
A The network between identified proteins is built using the STRING database using confidence level of 0.4 (default setting) and with no additional interactors. The edge color corresponds to the confidence score depending on the database, as defined in the legend. The gray edges are added to the network and represent the novel protein-protein interaction network identified by our study. Node position and edge length and width are created arbitrarily. B The top scoring IPA protein networks ‘Gene expression, RNA Damage and Repair, RNA Post-Transcriptional Modification’ is depicted for the highly enriched proteins in MEF2A complex in PCMs. The shape of the node represents the molecular type of the proteins as defined in the legend. The red color intensity represents the magnitude of enrichment of the protein in the MEF2A complex. The protein interaction networks were generated with IPA (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/). STAT3 gene is marked by a black star in both networks.
