Fig. 7: Remodeling of the NLRP3/IL33/ST2 axis by Honokiol (HNK) modulates the crosstalk between renal resident macrophages and renal tubular epithelial cells in lupus nephritis. | Cell Death & Disease

Fig. 7: Remodeling of the NLRP3/IL33/ST2 axis by Honokiol (HNK) modulates the crosstalk between renal resident macrophages and renal tubular epithelial cells in lupus nephritis.

From: Honokiol suppresses the aberrant interactions between renal resident macrophages and tubular epithelial cells in lupus nephritis through the NLRP3/IL-33/ST2 axis

Fig. 7: Remodeling of the NLRP3/IL33/ST2 axis by Honokiol (HNK) modulates the crosstalk between renal resident macrophages and renal tubular epithelial cells in lupus nephritis.The alternative text for this image may have been generated using AI.

A Co-culture of kTMs and NRK-52E cells, and protein levels in NRK-52E cells (n = 3, *p < 0.05, **p < 0.01) B Co-localization of CX3CR1, NLRP3, and ST2 in the mouse kidney. 400×; scale, 20 µm. C Molecular docking of HNK and NLRP3. D The binding sensorgram (for the interactions between HNK and NLRP3).

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