Fig. 5: Fpn1 knockout in ECs decreases cerebral iron levels during the early recovery stage of ischemic stroke. | Cell Death & Disease

Fig. 5: Fpn1 knockout in ECs decreases cerebral iron levels during the early recovery stage of ischemic stroke.

From: Cdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke

Fig. 5: Fpn1 knockout in ECs decreases cerebral iron levels during the early recovery stage of ischemic stroke.The alternative text for this image may have been generated using AI.

A The total iron content in the cortex detected by ICP-MS at Day 7 after dMCAO. B Representative western blot images of the levels of FtL, FtH, TfR1, and FPN1 in the contralateral (Con) and ipsilateral (Ips) cerebral cortex at Day 7 after dMCAO. Quantification of the western blot signals of FtL (C), FtH (D), TfR1 (E), and FPN1 (F). β-actin or GAPDH was used as an internal control. The data are presented as the mean ± SD. n = 6, two-way ANOVA, Tukey’s post hoc comparisons. *p < 0.05, **p < 0.01, ***p < 0.001.

Back to article page