Fig. 6: The existence of STAT1 is essential for the CDKL3-induced regulation of prostate cancer.
From: Inhibition of CDKL3 downregulates STAT1 thus suppressing prostate cancer development
A The cell proliferation rate of DU 145 cells with mere CDKL3 overexpression, mere STAT1 knockdown, or both, was evaluated by MTT assay. B The colony formation ability of DU 145 cells with mere CDKL3 overexpression, mere STAT1 knockdown, or both, was assessed by colony formation assay. C The percentage of apoptotic in DU 145 cells with mere CDKL3 overexpression, mere STAT1 knockdown, or both, was detected by flow cytometry. Data were presented as mean with standard deviation. P < 0.01, ***P < 0.001.
