Fig. 6: DDX23 knockdown led to suppressed in vivo tumor growth and lung metastasis. | Cell Death & Disease

Fig. 6: DDX23 knockdown led to suppressed in vivo tumor growth and lung metastasis.

From: METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation

Fig. 6

A–C The size (A), weight (B), and volume (C) of the in vivo tumors showed that DDX23 knockdown led to suppressed tumor growth in synergy with gemcitabine treatment. D H&E and Ki-67 IHC results showed that DDX23 knockdown led to suppressed tumor growth. E DDX23 knockdown led to suppressed lung metastasis, shown by the inhibited numbers of lung nodules. *P < 0.05, **P < 0.01, ***P < 0.001.

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