Fig. 1: The process of N-glycosylation.
From: The role of N-glycosylation modification in the pathogenesis of liver cancer
N-glycosylation modifications begin at the endoplasmic reticulum and end at the Golgi apparatus. The new oligosaccharide chains are initially processed in the endoplasmic reticulum and then transferred to the N-glycosylation sites of the new peptide chains by the action of the oligosaccharyltransferase complex (OST), and the attached polypeptide chains will undergo further processing and modification in the Golgi apparatus to form three N-glycan types, oligomannose, hybrid, and complex.
