Fig. 5: Proteomic study of the effect of rat Igh6 KO in DI TNC1 astrocyte cell line. | Cell Death & Disease

Fig. 5: Proteomic study of the effect of rat Igh6 KO in DI TNC1 astrocyte cell line.

From: Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion

Fig. 5

A Immunofluorescence with anti-IgG carried out on control and Igh6-2 KO DI TNC1 cells. B Venn diagram of the specific proteins identified in DI TNC1 cells after Igh6-1 KO, Igh6-2 KO, infection with an empty vector (EV), control cells treated or not with polybrene and Trop2 KO as a non-target control by Shotgun analyses (n = 3). C Heatmap representative of the proteins displaying a variation of abundance in DI TNC1 cells after Igh6-1 KO, Igh6-2 KO, Heimdall KO (KO2), control cells treated or not with polybrene, infection with EV and Trop2 KO as a non-target control, (n = 3). D Systemic biology representative of the specific cluster common to Igh6-1 KO, Igh6-2 KO, and Heimdall KO (KO2).

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