Fig. 3: Roles of TAMs in the TME and the molecules concerned. | Cell Death & Disease

Fig. 3: Roles of TAMs in the TME and the molecules concerned.

From: Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma

Fig. 3

TAMs play a significant role in glioma progression by contributing to glioma proliferation, vascularization, and invasion, promoting immunosuppression in the GME, generating treatment resistance, and influencing glioma metabolism. Acting through specific signaling pathways, various molecules are closely involved. Detailed mechanisms are discussed as follows. (By Figdraw).

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