Fig. 1: Cry2 is a substrate of acetylation which is driven by p300.
From: Cryptochrome 2 acetylation attenuates its antiproliferative effect in breast cancer
A Endogenous Cry2 is targeted by acetylation in MCF7 cells. B p300 promoted Cry2 acetylation in HEK293T cells. C Endogenous interaction between Cry2 and p300 in MCF7 cells. D Exogenous interaction between Cry2 and p300 in HEK293T cells. E p300 promoted Cry2 acetylation depend on its KAT activity. F p300 promoted Cry2 acetylation in a dose-dependent manner. G Cry2 and p300 were colocalized in the nucleus in MCF7 cells.
