Fig. 2: The KDAC of Cry2 is HDAC6.
From: Cryptochrome 2 acetylation attenuates its antiproliferative effect in breast cancer
A HDACs inhibitors increased Cry2 acetylation. B Endogenous interaction between Cry2 and HDAC6 in MCF7 cells. C Exogenous interaction between Cry2 and HDAC6 in HEK293T cells. D HDAC6 inhibitors increased Cry2 acetylation. E HDAC6 inhibited Cry2 acetylation depend on its KDAC activity. F HDAC6 decreased Cry2 acetylation in a dose-dependent manner. G Cry2 and HDAC6 were colocalized in the cytoplasm in MCF7 cells.
