Fig. 4: Acetylation leads to Cry2 stabilization.
From: Cryptochrome 2 acetylation attenuates its antiproliferative effect in breast cancer
A TSA promoted Cry2 stability. B p300 promoted Cry2 stability in a dose-dependent manner. C HDAC6 impaired Cry2 stability in a dose-dependent manner. D Cry2–3KR increased poly-ubiquitination of Cry2. E HDAC6 could not alter the ubiquitination of Cry2–3KR. F Half-lives of Cry2 and mutants.
