Fig. 1: CMTR1 expression positively correlates with the progression of colorectal cancer. | Cell Death & Disease

Fig. 1: CMTR1 expression positively correlates with the progression of colorectal cancer.

From: CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3

Fig. 1

A Analysis of CMTR1 expression in human colon cancer tissues (n = 480) and adjacent normal tissues (n = 41) based on a TCGA dataset. B Analysis of CMTR1 expression in paired human colon cancer tissues (n = 41) and adjacent normal tissues (n = 41) based on a TCGA dataset. C Relative expression of CMTR1 in normal individuals and in COAD patients with tumors of different pathologic stages. D Kaplan‒Meier survival curves of overall survival (OS) in the TCGA-COAD cohort. E–H The CMTR1 protein levels in CRC tumor tissues (T) and matched adjacent normal tissues (N) were measured by western blotting. I Representative images of immunohistochemical staining for CMTR1 in CRC tumor tissues (n = 71) and matched adjacent normal tissues (scale bar, 200 μm). J CMTR1 expression scores are shown on box plots. The data were analysed using the Kruskal‒Wallis test. K Kaplan‒Meier survival curves of overall survival (OS) in our patient cohort stratified by CMTR1 staining. L Representative images of immunohistochemical staining to evaluate CMTR1 protein expression in colorectal cancer tissues at four clinical stages (scale bar, 40 μm). *P < 0.05, **P < 0.01, and ***P < 0.001.

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