Fig. 5: CMTR1-regulated tumor cell proliferation and immune responses are STAT3-dependent.

A–G Changes of STAT3 knockdown on CMTR1-induced inflammatory mediators. H–J Effect of STAT3 knockdown on CMTR1-induced tumor cell proliferation, as assessed by CCK8, colony formation, and EdU incorporation assays (scale bar, 50 μm). *P < 0.05, **P < 0.01, and ***P < 0.001.