Fig. 2: PRMT2 promotes RCC cell proliferation and migration.
From: PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression
A–D PRMT2 expression was assessed by western blots in ACHN and 786-O cell lines after knockdown (A) or overexpression (C) of PRMT2, followed by CCK-8 assays (B, D). E–H Flow cytometry was used to detect and quantify cell cycle arrest in ACHN and 786-O cell lines after knockdown (E) or overexpression (G) of PRMT2, and cell cycle-related proteins were assessed by western blots (F, H). I–L Detection of RCC cell migration by Transwell assays in ACHN and 786-O cells after knockdown (I) or overexpression (K) of PRMT2. Biomarkers of EMT were assessed by western blots after knockdown (J) or overexpression (L) of PRMT2. Data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001.
