Fig. 1: The expression of RNF128 is upregulated in the lungs of LPS-treated mice.
From: RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury
A Experimental scheme for determining neutrophilic inflammatory response and RNF128 in the ALI model. B The expression of Neutrophil Elastase, Caspase 3, Cleaved Caspase 3 and PARP protein in the lungs of mice treated with PBS (WT + PBS, n = 4) or LPS (WT + LPS, n = 4) for 24 h. C The levels of RNF128, TNF-α, IL-1ß and MMP9 mRNAs were measured using Q-PCR. D RNF128 protein expression in the lungs of mice treated with PBS (WT + PBS, n = 4) or LPS (WT + LPS, n = 4) for 24 h. The statistical significance was evaluated using Student’s t-test. ***P < 0.001, Student’s t-test.
