Fig. 3: The effect of LIMD1-AS1 on the malignant phenotype of glioma cells. | Cell Death & Disease

Fig. 3: The effect of LIMD1-AS1 on the malignant phenotype of glioma cells.

From: Super-enhancer-driven lncRNA LIMD1-AS1 activated by CDK7 promotes glioma progression

Fig. 3

A Expression of LIMD1-AS1 in LN-18 and T98G cells transfected si-LIMD1-AS1 as measured by RT-qPCR. **P < 0.01. B, C CCK8 assays were performed to examine the proliferation in LN-18 and T98G cells transfected with two different siRNAs. **P < 0.01. D, E Transwell assays were performed to observe the number of migrated cells in LN-18 and T98G cells transfected with two different siRNAs. **P < 0.01. F, G Transwell assays were performed to observe the number of invaded cells in LN-18 and T98G cells transfected with two different siRNAs. **P < 0.01. H LIMD1-AS1 expression in SF126 cells transfected LIMD1-AS1 plasmid as measured by qPCR. **P < 0.01. I, J LIMD1-AS1 overexpression cells increased clone formation ability. **P < 0.01. K–N Transwell assays were performed to examine the number of migrated or invaded cells in SF126 cells transfected with LIMD1-AS1 plasmid. **P < 0.01. O–P Western blotting results for the protein level of proliferation and EMT-associated markers in SF126 glioma cells transfected with vector/LIMD1-AS1. **P < 0.01.

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