Fig. 8: TIMM13 KO inhibits in situ OS xenograft growth.
From: HOXC13-driven TIMM13 overexpression promotes osteosarcoma cell growth
The parental control pOS-1 cells or the koTIMM13 pOS-1 cells were injected into the proximal tibia of the nude mice. After 28 days, in situ pOS-1 xenografts were formed and tumor volumes were measured under X-ray (A); expression of listed genes and proteins in the listed in situ tumor lysates was shown (B–D, G); ATP contents (E) and the TBAR activity (F) in the tumor lysates were tested as well. The representative TUNEL fluorescence images of in situ xenograft slides were presented as well, with TUNEL ratio quantified (H). Error bars stand for mean ± standard deviation (SD). Scale bar = 100 μm (H).
