Fig. 7: circTBPL1 promotes malignant behaviors of breast cancer cells via regulating TPBG expression.

Breast cancer cells were co-transfected with circTBPL1 overexpression vectors and TPBG siRNA. A The RNA and protein expression of TPBG was detected using qRT-PCR and western blot. B–D The proliferation ability of breast cancer cells was evaluated by MTT assay (B), colony formation assay (C), and Edu assay (D). E Wound healing assay was performed to investigate the migration ability of breast cancer cells. F Transwell assay was used to evaluate the migration and invasion abilities of breast cancer cells. (ns, no significance, *P < 0.05, **P < 0.01, ***P < 0.001).