Fig. 6: Increased ASNS is positively associated with NUCKS1 expression in osteosarcoma. | Cell Death & Disease

Fig. 6: Increased ASNS is positively associated with NUCKS1 expression in osteosarcoma.

From: NUCKS1, a LINC00629-upregulated gene, facilitated osteosarcoma progression and metastasis by elevating asparagine synthesis

Fig. 6: Increased ASNS is positively associated with NUCKS1 expression in osteosarcoma.The alternative text for this image may have been generated using AI.

A The expression levels of ASNS in osteosarcoma (n = 88) and normal tissues (n = 564) were analyzed from the TNMplot database. B, C Representative microphotographs of ASNS immunohistochemical staining of normal bone tissues and osteosarcoma tissue sections (B). The expression of ASNS in normal bone tissues and osteosarcoma tissue was assessed (C). D The relationship between ASNS expression and tumor staging was analyzed. E Kaplan–Meier plot of the overall survival rate of 262 patients with sarcoma. The data were obtained from the GEPIA database. F Kaplan–Meier plot of the overall survival rate of 259 patients with sarcoma. The data were obtained from the Kaplan–Meier Plotter. G, H Representative microphotographs of ASNS immunohistochemical staining of osteosarcoma tissues and the correction between ASNS and NUCKS1 were analyzed. Data in C, D and H were analyzed by Student’s t test, *p < 0.05, **p < 0.01, ***p < 0.001.

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